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Objective To verify the applicability of mental health dual-factor theory in normal population and understand the mental health of them.Methods According to Keyes' theory of mental health,the questionnaire was used to investigate the negative and positive psychological health of 1900 normal population.Then,confirmatory factor analysis was carried out.Result The fitting index of the dual-Factor model in Zhejiang group was more ideal by comparing the different models(x2/df=3.63,RMR=0.04,RMSEA =0.095).In the people of Zhejiang province,69.8％ were completely mentally healthy,9.4％ were troubled,7.3％ were vulnerable,13.5％ were symptomatic but content.The distribution results were consistent with those of foreign researches.The results between the six-point method and Keyes' method were significantly different(x2=187.5,P＜0.01).In this study,a combination of PHQ-9,GAD-7 and GHQ-12 was used in the study,and 22.9％ of the population were screened for mental illness.Conclusion The dual-Factor model of mental health is suitable for normal population.Mental health can be assessed by warwick-edinburgh mental well-being scale(WEMWBS),PHQ-9,GAD-7 and GHQ-12.
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the -3826A/G polymorphism in the promoter of the uncoupling protein-1 (UCP1) gene and its relations to obesity in Chinese population.</p><p><b>METHODS</b>Three hundred and eighty-four subjects (257 non-obese and 127 obese individuals) from a population of Chinese Han nationality in Chengdu area were studied using polymerase chain reaction-restriction fragment length polymorphisms (PCR-RFLPs). Serum lipids were measured by enzymatic kits and apolipoproteins A I, A II, B100, C II, C III and E were measured by the RID kits.</p><p><b>RESULTS</b>The frequencies of A and G alleles at -3826A/G site in obese and non-obese groups were 0.508 and 0.492, and 0.467 and 0.533, respectively. It showed no significant difference in allele frequencies between non-obese and obese groups (P > 0.05). In the obese group, subjects with genotype GG had higher serum apo B100 concentrations, and those with genotype AG had higher apo C II and apo C III levels, than those with genotype AA, respectively (P < 0.05). In non-obese male subgroup, subjects with genotype GG had lower serum HDL-C and apo A I levels than those with genotype AA, respectively (P < 0.05), whereas those with genotype AG had lower apo A II levels than those with genotype AA. In addition, in obese males with genotype GG had elevated apo B100 levels compared with those with genotype AA, whereas in obese females with genotype GG had decreased apo AI levels and genotype AG had increased apo C II and apo C III levels compared with those with genotype AG and AA, respectively (P < 0.05).</p><p><b>CONCLUSION</b>-3826A/G polymorphism in the promoter of the uncoupling protein-1 gene was not associated with obesity in Chinese Han population of Chengdu area. It may be associated with serum HDL-C, apo A I and apo B100 levels in non-obese and/or obese subjects of certain genders.</p>